Plant expansins are structural cell wall-loosening proteins implicated in a number of developmental processes and responses to environmental constraints and pathogen an infection. To date, there may be restricted details about the organic operate of Expansins-like B (EXLBs), one of the smallest and less-studied subfamilies of plant expansins. In the current examine, we performed a useful evaluation of the wild Arachis AdEXLB8 gene in transgenic tobacco (Nicotiana tabacum) vegetation to make clear its putative position in mediating protection responses to abiotic and biotic stresses.
First, its cell wall localization was confirmed in vegetation expressing AdEXLB8:eGFP fusion, whereas nanomechanical assays indicated cell wall reorganization and reassembly due to AdEXLB8 overexpression with out compromising the phenotype. We additional demonstrated that AdEXLB8 elevated tolerance not solely to remoted abiotic (drought) and biotic (Sclerotinia sclerotiorum and Meloidogyne incognita) stresses but in addition to their mixture.
The jasmonate and abscisic acid signaling pathways have been clearly favored in transgenic vegetation, exhibiting an activated antioxidative protection system. In addition to modifications within the biomechanical properties of the cell wall, we suggest that AdEXLB8 overexpression interferes with phytohormone dynamics main to a protection primed state, which culminates in plant protection responses in opposition to remoted and mixed abiotic and biotic stresses.
Ddx20, DEAD field helicase 20, is crucial for the differentiation of oligodendrocyte and upkeep of myelin gene expression
Oligodendrocytes kind myelin sheaths that encompass axons, contributing to saltatory conduction and correct central nervous system (CNS) operate. Oligodendrocyte progenitor cells (OPCs) are generated in the course of the embryonic stage and differentiate into myelinating oligodendrocytes postnatally. Ddx20 is a multifunctional, DEAD-box helicase concerned in a number of mobile processes, together with transcription, splicing, microRNA biogenesis, and translation.
Although defects in every of these processes lead to irregular oligodendrocyte differentiation and myelination, the involvement of Ddx20 in oligodendrocyte terminal differentiation stays unknown. To tackle this query, we used Mbp-Cre mice to generate Ddx20 conditional knockout (cKO) mice to permit for the deletion of Ddx20 from mature oligodendrocytes. Mbp-Cre;Ddx20 cKO mice demonstrated small physique sizes, behavioral abnormalities, muscle weak point, and quick lifespans, with mortality by the age of 2 months outdated.
Histological analyses demonstrated vital reductions within the quantity of mature oligodendrocytes and drastic reductions within the expression ranges of myelin-associated mRNAs, similar to Mbp and Plp at postnatal day 42. The quantity of OPCs didn’t change. A skinny myelin layer was noticed for large-diameter axons in Ddx20 cKO mice, based mostly on electron microscopic evaluation.
A bromodeoxyuridine (BrdU) labeling experiment demonstrated that terminal differentiation was perturbed from ages 2 weeks to 7 weeks within the CNS of Mbp-Cre;Ddx20 cKO mice. The activation of mitogen-activated protein (MAP) kinase, which promotes myelination, was downregulated within the Ddx20 cKO mice based mostly on immunohistochemical detection. These outcomes point out that Ddx20 is an important issue for terminal differentiation of oligodendrocytes and upkeep of myelin gene expression.
SUMO Paralog Specific Functions Revealed via Systematic Analysis of Human Knockout Cell Lines and Gene Expression Data
The small ubiquitin-related modifiers (SUMOs) regulate practically each facet of mobile operate, from gene expression within the nucleus to ion transport on the plasma membrane. In people, the SUMO pathway has 5 SUMO paralogs with sequence homologies that vary from 45% to 97%. SUMO1 and SUMO2 are probably the most distantly associated paralogs, and additionally the perfect studied.
To what extent SUMO1, SUMO2 and the opposite paralogs impart distinctive and non-redundant results on mobile features, nonetheless, has not been systematically examined and is due to this fact not totally understood. For occasion, knockout research in mice have revealed conflicting necessities for the paralogs throughout improvement and research in cell tradition have relied largely on transient paralog overexpression or knockdown.
To tackle the prevailing hole in understanding, we first analyzed SUMO paralog gene expression ranges in regular human tissues and discovered distinctive patterns of SUMO1-3 expression throughout 30 tissue varieties, suggesting paralog-specific features in grownup human tissues. To systematically determine and characterize distinctive and non-redundant features of the SUMO paralogs in human cells, we subsequent used CRISPR-Cas9 to knock out SUMO1 and SUMO2 expression in osteosarcoma (U2OS) cells.
Analysis of these knockout cell traces revealed important features for SUMO1 and SUMO2 in regulating mobile morphology, PML nuclear physique construction, responses to proteotoxic and genotoxic stress, and management of gene expression. Collectively, our findings reveal non-redundant regulatory roles for SUMO1 and SUMO2 in controlling important mobile processes and present a foundation for extra exact SUMO-targeting therapies.

High-dimensional covariance matrices exams for analyzing multi-tumor gene expression information
By amassing a number of units per topic in microarray information, gene units evaluation requires characterize intra-subject variation utilizing gene expression profiling. For every topic, the info might be written as a matrix with the totally different subsets of gene expressions (e.g. a number of tumor varieties) indexing the rows and the genes indexing the columns.
Human FYN Oncogene Related To SRC/FGR/YES (FYN) ELISA Kit |
RD-FYN-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 625.2 |
Human FYN Oncogene Related To SRC/FGR/YES (FYN) ELISA Kit |
RD-FYN-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 867.6 |
Mouse FYN Oncogene Related To SRC/FGR/YES (FYN) ELISA Kit |
RD-FYN-Mu-48Tests |
Reddot Biotech |
48 Tests |
EUR 639.6 |
Mouse FYN Oncogene Related To SRC/FGR/YES (FYN) ELISA Kit |
RD-FYN-Mu-96Tests |
Reddot Biotech |
96 Tests |
EUR 888 |
FYN Antibody / Tyrosine-protein kinase Fyn |
RQ5137 |
NSJ Bioreagents |
100ul |
EUR 419 |
FYN Antibody |
43186-100ul |
SAB |
100ul |
EUR 302.4 |
FYN antibody |
70R-49768 |
Fitzgerald |
100 ul |
EUR 344.4 |
Description: Purified Polyclonal FYN antibody |
FYN antibody |
70R-5772 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Rabbit polyclonal FYN antibody raised against the N terminal of FYN |
FYN antibody |
70R-31289 |
Fitzgerald |
100 ug |
EUR 392.4 |
Description: Rabbit polyclonal FYN antibody |
FYN Peptide |
45-059P |
ProSci |
0.1 mg |
EUR 405.6 |
Description: (NT) FYN Peptide |
FYN antibody |
10R-10608 |
Fitzgerald |
100 ug |
EUR 418.8 |
Description: Mouse monoclonal FYN antibody |
FYN antibody |
10R-11001 |
Fitzgerald |
100 ug |
EUR 418.8 |
Description: Mouse monoclonal FYN antibody |
FYN antibody |
70R-5867 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Rabbit polyclonal FYN antibody raised against the middle region of FYN |
FYN Antibody |
1-CSB-PA225018 |
Cusabio |
|
|
|
Description: A polyclonal antibody against FYN. Recognizes FYN from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;ELISA:1:2000-1:5000, WB:1:500-1:2000 |
FYN Antibody |
1-CSB-PA143385 |
Cusabio |
|
|
|
Description: A polyclonal antibody against FYN. Recognizes FYN from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;ELISA:1:2000-1:5000, WB:1:500-1:2000 |
FYN Antibody |
1-CSB-PA002595 |
Cusabio |
|
|
|
Description: A polyclonal antibody against FYN. Recognizes FYN from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/5000 |
FYN Antibody |
1-CSB-PA008520 |
Cusabio |
|
|
|
Description: A polyclonal antibody against FYN. Recognizes FYN from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/10000 |
FYN Antibody |
1-CSB-PA009101LA01HU |
Cusabio |
|
|
|
Description: A polyclonal antibody against FYN. Recognizes FYN from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200 |
anti-Fyn |
YF-PA23745 |
Abfrontier |
50 ul |
EUR 400.8 |
Description: Mouse polyclonal to Fyn |
anti-Fyn |
YF-PA23746 |
Abfrontier |
50 ul |
EUR 400.8 |
Description: Mouse polyclonal to Fyn |
anti-Fyn |
YF-PA11887 |
Abfrontier |
50 ul |
EUR 435.6 |
Description: Mouse polyclonal to Fyn |
anti-Fyn |
YF-PA11888 |
Abfrontier |
100 ug |
EUR 483.6 |
Description: Rabbit polyclonal to Fyn |
Monoclonal SYN / FYN Antibody (aa7-176, clone FYN-59), Clone: FYN-59 |
AMM01704G |
Leading Biology |
0.05mg |
EUR 580.8 |
Description: A Monoclonal antibody against Human SYN / FYN (aa7-176, clone FYN-59). The antibodies are raised in Mouse and are from clone FYN-59. This antibody is applicable in WB and IHC-P, IP |
Monoclonal SYN / FYN Antibody (aa7-176, clone FYN-01), Clone: FYN-01 |
AMM01732G |
Leading Biology |
0.05mg |
EUR 580.8 |
Description: A Monoclonal antibody against Human SYN / FYN (aa7-176, clone FYN-01). The antibodies are raised in Mouse and are from clone FYN-01. This antibody is applicable in WB and IHC-P, ICC, IP |
Chymase reagent |
30C-CP1129 |
Fitzgerald |
5 units |
EUR 2622 |
Description: Purified native Human Chymase reagent |
Traut's Reagent |
2330-1000 |
Biovision |
|
EUR 418.8 |
BOP reagent |
A7015-100000 |
ApexBio |
100 g |
EUR 240 |
Description: A peptide coupling reagent. Can be used in the preparation of phenyl esters of amino acids which have been shown to be valuable as blocked derivatives of amino acids in the field of peptide synthesis. |
BOP reagent |
A7015-25000 |
ApexBio |
25 g |
EUR 135.6 |
Description: A peptide coupling reagent. Can be used in the preparation of phenyl esters of amino acids which have been shown to be valuable as blocked derivatives of amino acids in the field of peptide synthesis. |
Bradford reagent |
BDE641 |
Bio Basic |
100ml |
EUR 73.21 |
|
Human Tyrosine-Protein Kinase Fyn (FYN) ELISA Kit |
20-abx151604 |
Abbexa |
-
EUR 8853.60
-
EUR 4719.60
-
EUR 1093.20
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
Mouse Tyrosine-Protein Kinase Fyn (FYN) ELISA Kit |
20-abx154045 |
Abbexa |
-
EUR 8853.60
-
EUR 4719.60
-
EUR 1093.20
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
Rat Tyrosine-Protein Kinase Fyn (FYN) ELISA Kit |
abx391361-96tests |
Abbexa |
96 tests |
EUR 1093.2 |
|
Goat Tyrosine protein kinase Fyn(FYN) ELISA kit |
E06T0613-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Goat Tyrosine protein kinase Fyn(FYN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Tyrosine protein kinase Fyn(FYN) ELISA kit |
E06T0613-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Goat Tyrosine protein kinase Fyn(FYN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Tyrosine protein kinase Fyn(FYN) ELISA kit |
E06T0613-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Goat Tyrosine protein kinase Fyn(FYN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Tyrosine protein kinase Fyn(FYN) ELISA kit |
E04T0613-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Rabbit Tyrosine protein kinase Fyn(FYN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Tyrosine protein kinase Fyn(FYN) ELISA kit |
E04T0613-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Rabbit Tyrosine protein kinase Fyn(FYN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Tyrosine protein kinase Fyn(FYN) ELISA kit |
E04T0613-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Rabbit Tyrosine protein kinase Fyn(FYN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Tyrosine protein kinase Fyn(FYN) ELISA kit |
E03T0613-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Mouse Tyrosine protein kinase Fyn(FYN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Tyrosine protein kinase Fyn(FYN) ELISA kit |
E03T0613-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Mouse Tyrosine protein kinase Fyn(FYN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Tyrosine protein kinase Fyn(FYN) ELISA kit |
E03T0613-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Mouse Tyrosine protein kinase Fyn(FYN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Tyrosine protein kinase Fyn(FYN) ELISA kit |
E09T0613-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Monkey Tyrosine protein kinase Fyn(FYN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Tyrosine protein kinase Fyn(FYN) ELISA kit |
E09T0613-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Monkey Tyrosine protein kinase Fyn(FYN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Tyrosine protein kinase Fyn(FYN) ELISA kit |
E09T0613-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Monkey Tyrosine protein kinase Fyn(FYN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Tyrosine protein kinase Fyn(FYN) ELISA kit |
E02T0613-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Rat Tyrosine protein kinase Fyn(FYN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Tyrosine protein kinase Fyn(FYN) ELISA kit |
E02T0613-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Rat Tyrosine protein kinase Fyn(FYN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Tyrosine protein kinase Fyn(FYN) ELISA kit |
E02T0613-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Rat Tyrosine protein kinase Fyn(FYN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Tyrosine protein kinase Fyn(FYN) ELISA kit |
E08T0613-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Canine Tyrosine protein kinase Fyn(FYN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Tyrosine protein kinase Fyn(FYN) ELISA kit |
E08T0613-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Canine Tyrosine protein kinase Fyn(FYN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Tyrosine protein kinase Fyn(FYN) ELISA kit |
E08T0613-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Canine Tyrosine protein kinase Fyn(FYN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Chicken Tyrosine- protein kinase Fyn, FYN ELISA KIT |
ELI-27562c |
Lifescience Market |
96 Tests |
EUR 1113.6 |
Human Tyrosine- protein kinase Fyn, FYN ELISA KIT |
ELI-27563h |
Lifescience Market |
96 Tests |
EUR 988.8 |
Porcine Tyrosine- protein kinase Fyn, FYN ELISA KIT |
ELI-47364p |
Lifescience Market |
96 Tests |
EUR 1113.6 |
Bovine Tyrosine- protein kinase Fyn, FYN ELISA KIT |
ELI-30932b |
Lifescience Market |
96 Tests |
EUR 1113.6 |
Mouse Tyrosine- protein kinase Fyn, Fyn ELISA KIT |
ELI-37594m |
Lifescience Market |
96 Tests |
EUR 1038 |
Human Tyrosine protein kinase Fyn(FYN) ELISA kit |
E01T0613-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Human Tyrosine protein kinase Fyn(FYN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Tyrosine protein kinase Fyn(FYN) ELISA kit |
E01T0613-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Human Tyrosine protein kinase Fyn(FYN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Tyrosine protein kinase Fyn(FYN) ELISA kit |
E01T0613-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Human Tyrosine protein kinase Fyn(FYN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Tyrosine protein kinase Fyn(FYN) ELISA kit |
E07T0613-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Porcine Tyrosine protein kinase Fyn(FYN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Tyrosine protein kinase Fyn(FYN) ELISA kit |
E07T0613-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Porcine Tyrosine protein kinase Fyn(FYN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Tyrosine protein kinase Fyn(FYN) ELISA kit |
E07T0613-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Porcine Tyrosine protein kinase Fyn(FYN) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
HEK-293T Telomerase Over-Expressing Cell Pellet |
abx069991-1Pellet |
Abbexa |
1 Pellet |
EUR 477.6 |
|
FYN Mouse mAb |
A0086-100ul |
Abclonal |
100 ul |
EUR 460.8 |
FYN Mouse mAb |
A0086-200ul |
Abclonal |
200 ul |
EUR 664.8 |
FYN Mouse mAb |
A0086-20ul |
Abclonal |
20 ul |
Ask for price |
FYN Mouse mAb |
A0086-50ul |
Abclonal |
50 ul |
EUR 318 |
Fyn antibody (Tyr530) |
70R-37433 |
Fitzgerald |
100 ug |
EUR 418.8 |
Description: Rabbit Polyclonal Fyn antibody (Tyr530) |
FYN antibody (Tyr530) |
70R-31288 |
Fitzgerald |
100 ug |
EUR 392.4 |
Description: Rabbit polyclonal FYN antibody (Tyr530) |
FYN Blocking Peptide |
33R-1771 |
Fitzgerald |
100 ug |
EUR 216 |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of FYN antibody, catalog no. 70R-5867 |
FYN Blocking Peptide |
33R-3193 |
Fitzgerald |
100 ug |
EUR 216 |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of FYN antibody, catalog no. 70R-5772 |
Fyn Polyclonal Antibody |
40943-100ul |
SAB |
100ul |
EUR 302.4 |
Fyn Polyclonal Antibody |
40943-50ul |
SAB |
50ul |
EUR 224.4 |
Anti-FYN Purified |
11-375-C025 |
ExBio |
0.025 mg |
EUR 146.4 |
Anti-FYN Purified |
11-375-C100 |
ExBio |
0.1 mg |
EUR 244.8 |
Fyn Polyclonal Antibody |
ABP54417-003ml |
Abbkine |
0.03ml |
EUR 189.6 |
|
Description: A polyclonal antibody for detection of Fyn from Human, Mouse, Rat. This Fyn antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Fyn around the non-phosphorylation site of Y213 |
Fyn Polyclonal Antibody |
ABP54417-01ml |
Abbkine |
0.1ml |
EUR 346.8 |
|
Description: A polyclonal antibody for detection of Fyn from Human, Mouse, Rat. This Fyn antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Fyn around the non-phosphorylation site of Y213 |
Fyn Polyclonal Antibody |
ABP54417-02ml |
Abbkine |
0.2ml |
EUR 496.8 |
|
Description: A polyclonal antibody for detection of Fyn from Human, Mouse, Rat. This Fyn antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Fyn around the non-phosphorylation site of Y213 |
FYN (pT530) Antibody |
20-abx009886 |
Abbexa |
-
EUR 376.80
-
EUR 560.40
-
EUR 243.60
|
|
|
FYN (pS21) Antibody |
20-abx123287 |
Abbexa |
-
EUR 594.00
-
EUR 844.80
-
EUR 260.40
-
EUR 427.20
|
- 100 ul
- 200 ul
- 20 ul
- 50 ul
|
|
FYN (pY416) Antibody |
20-abx123288 |
Abbexa |
-
EUR 594.00
-
EUR 844.80
-
EUR 260.40
-
EUR 427.20
|
- 100 ul
- 200 ul
- 20 ul
- 50 ul
|
|
Fyn Polyclonal Antibody |
ABP51383-003ml |
Abbkine |
0.03ml |
EUR 189.6 |
|
Description: A polyclonal antibody for detection of Fyn from Human, Mouse, Rat. This Fyn antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Fyn around the non-phosphorylation site of Y530 |
Fyn Polyclonal Antibody |
ABP51383-01ml |
Abbkine |
0.1ml |
EUR 346.8 |
|
Description: A polyclonal antibody for detection of Fyn from Human, Mouse, Rat. This Fyn antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Fyn around the non-phosphorylation site of Y530 |
Fyn Polyclonal Antibody |
ABP51383-02ml |
Abbkine |
0.2ml |
EUR 496.8 |
|
Description: A polyclonal antibody for detection of Fyn from Human, Mouse, Rat. This Fyn antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Fyn around the non-phosphorylation site of Y530 |
Fyn (pY530) Antibody |
abx010767-100ug |
Abbexa |
100 ug |
EUR 526.8 |
|
FYN Mouse pAb |
A18127-100ul |
Abclonal |
100 ul |
EUR 369.6 |
FYN Mouse pAb |
A18127-200ul |
Abclonal |
200 ul |
EUR 550.8 |
FYN Mouse pAb |
A18127-20ul |
Abclonal |
20 ul |
EUR 219.6 |
FYN Mouse pAb |
A18127-50ul |
Abclonal |
50 ul |
EUR 267.6 |
Fyn-p59 Protein |
20-abx263558 |
Abbexa |
-
EUR 994.80
-
EUR 493.20
-
EUR 644.40
|
|
|
FYN (pY530) Antibody |
abx333497-100ul |
Abbexa |
100 ul |
EUR 560.4 |
|
Monoclonal Fyn Antibody |
AMM03159G |
Leading Biology |
0.1ml |
EUR 580.8 |
Description: A Monoclonal antibody against Human Fyn. The antibodies are raised in Mouse. This antibody is applicable in WB, ICC |
Fyn Blocking Peptide |
AF7697-BP |
Affbiotech |
1mg |
EUR 234 |
FYN Blocking Peptide |
BF0309-BP |
Affbiotech |
1mg |
EUR 234 |
FYN cloning plasmid |
CSB-CL009101HU-10ug |
Cusabio |
10ug |
EUR 279.6 |
|
Description: A cloning plasmid for the FYN gene. |
Fyn Blocking Peptide |
AF6102-BP |
Affbiotech |
1mg |
EUR 234 |
FYN Conjugated Antibody |
C43186 |
SAB |
100ul |
EUR 476.4 |
Fyn Polyclonal Antibody |
ES2382-100ul |
ELK Biotech |
100ul |
EUR 334.8 |
Description: A Rabbit Polyclonal antibody against Fyn from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
Fyn Polyclonal Antibody |
ES2382-50ul |
ELK Biotech |
50ul |
EUR 248.4 |
Description: A Rabbit Polyclonal antibody against Fyn from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
Recombinant Human FYN |
P0305 |
FN Test |
100ug |
EUR 626.83 |
|
Description: Recombinant Human protein for FYN |
anti-FYN (2A10) |
LF-MA30592 |
Abfrontier |
100 ul |
EUR 632.4 |
Description: Mouse Monoclonal to FYN |
anti-FYN (2H8) |
LF-MA30593 |
Abfrontier |
100 ul |
EUR 632.4 |
Description: Mouse Monoclonal to FYN |
Fyn Polyclonal Antibody |
ES5416-100ul |
ELK Biotech |
100ul |
EUR 334.8 |
Description: A Rabbit Polyclonal antibody against Fyn from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA |
Fyn Polyclonal Antibody |
ES5416-50ul |
ELK Biotech |
50ul |
EUR 248.4 |
Description: A Rabbit Polyclonal antibody against Fyn from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA |
Anti-Fyn Antibody |
PB9197 |
BosterBio |
100ug/vial |
EUR 352.8 |
Anti-FYN antibody |
STJ110903 |
St John's Laboratory |
100 µl |
EUR 471.6 |
Description: This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist. |
Anti-FYN antibody |
STJ11100097 |
St John's Laboratory |
100 µl |
EUR 332.4 |
Description: This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist. |
Anti-Fyn antibody |
STJ93170 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Rabbit polyclonal to Fyn. |
Anti-Fyn antibody |
STJ93171 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Fyn is a protein encoded by the FYN gene which is approximately 60,7 kDa. Fyn is localised to the cytoplasm, cell membrane and nucleus. It is involved in RET signalling, GAB1 signalosome, EPH-Ephrin signalling, HIV life cycle and the development Slit-Robo signalling. It is a membrane-associated tyrosine kinase that plays a role in the regulation of cell growth and survival, cell adhesion, integrin-mediated signalling, cytoskeletal remodelling, cell motility, immune response and axon guidance. Following activation by PKA, the protein subsequently associates with PTK2/FAK1, allowing PTK2/FAK1 phosphorylation, activation and targeting to focal adhesions. Fyn isoform 1 is highly expressed in the brain and isoform 2 is expressed in cells of hemopoietic lineages, especially T-lymphocytes. Mutations in the FYN gene may result in Wiskott-Aldrich syndrome. STJ93171 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Fyn protein. |
Anti-Fyn antibody |
STJ98091 |
St John's Laboratory |
100 µl |
EUR 280.8 |
Description: Mouse monoclonal to Fyn. |
Anti-Fyn antibody |
STJ98092 |
St John's Laboratory |
100 µl |
EUR 280.8 |
Description: Mouse monoclonal to Fyn. |
Anti-Fyn antibody |
STJ99129 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Mouse monoclonal to Fyn. |
Anti-Fyn (3A8) |
YF-MA13156 |
Abfrontier |
100 ug |
EUR 435.6 |
Description: Mouse monoclonal to Fyn |
Anti-Fyn (1A3) |
YF-MA13157 |
Abfrontier |
100 ug |
EUR 435.6 |
Description: Mouse monoclonal to Fyn |
Anti-Fyn (2G2) |
YF-MA13158 |
Abfrontier |
100 ug |
EUR 435.6 |
Description: Mouse monoclonal to Fyn |
FYN Polyclonal Antibody |
A59178-020 |
EpiGentek |
20 ul |
EUR 117.7 |
FYN Polyclonal Antibody |
A59178-050 |
EpiGentek |
50 ul |
EUR 302.5 |
FYN Polyclonal Antibody |
A59178-100 |
EpiGentek |
100 ul |
EUR 423.5 |
FYN Polyclonal Antibody |
A59178 |
EpiGentek |
-
EUR 684.66
-
EUR 117.70
-
EUR 302.50
-
EUR 423.50
|
- 100 µg
- 20 ul
- 50 ul
- 100 ul
|
Esophagus Lysate |
1365 |
ProSci |
0.1 mg |
EUR 229.2 |
Description: Esophagus tissue lysate was prepared by homogenization in lysis buffer (10 mM HEPES pH7.9, 1.5 mM MgCl2, 10 mM KCl, 1 mM ethylenediaminetetraacetic acid, 10% glycerol, 1% NP-40, and a cocktail of protease inhibitors). Tissue and cell debris was removed by centrifugation. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT. |
Ileum Lysate |
1367 |
ProSci |
0.1 mg |
EUR 229.2 |
Description: Ileum tissue lysate was prepared by homogenization in lysis buffer (10 mM HEPES pH7.9, 1.5 mM MgCl2, 10 mM KCl, 1 mM ethylenediaminetetraacetic acid, 10% glycerol, 1% NP-40, and a cocktail of protease inhibitors). Tissue and cell debris was removed by centrifugation. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT. |
Rectum Lysate |
1373 |
ProSci |
0.1 mg |
EUR 229.2 |
Description: Rectum tissue lysate was prepared by homogenization in homogenization in lysis buffer (10 mM HEPES pH7.9, 1.5 mM MgCl2, 10 mM KCl, 1 mM ethylenediaminetetraacetic acid, 10% glycerol, 1% NP-40, and a cocktail of protease inhibitors). Tissue and cell debris was removed by centrifugation. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT. |
Skin Lysate |
1376 |
ProSci |
0.1 mg |
EUR 229.2 |
Description: Skin tissue lysate was prepared by homogenization in lysis buffer (10 mM HEPES pH7.9, 1.5 mM MgCl2, 10 mM KCl, 1 mM ethylenediaminetetraacetic acid, 10% glycerol, 1% NP-40, and a cocktail of protease inhibitors). Tissue and cell debris was removed by centrifugation. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT. |
Thyroid Lysate |
1380 |
ProSci |
0.1 mg |
EUR 229.2 |
Description: Thyroid tissue lysate was prepared by homogenization in lysis buffer (10 mM HEPES pH7.9, 1.5 mM MgCl2, 10 mM KCl, 1 mM ethylenediaminetetraacetic acid, 10% glycerol, 1% NP-40, and a cocktail of protease inhibitors). Tissue and cell debris was removed by centrifugation. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT. |
Spleen Lysate |
1406 |
ProSci |
0.1 mg |
EUR 229.2 |
Description: Spleen tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT. |
Bladder Lysate |
1410 |
ProSci |
0.1 mg |
EUR 229.2 |
Description: Bladder tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT. |
Cerebellum Lysate |
1412 |
ProSci |
0.1 mg |
EUR 229.2 |
Description: Cerebellum tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT. |
Cerebrum Lysate |
1413 |
ProSci |
0.1 mg |
EUR 229.2 |
Description: Cerebrum tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT. |
Pancreas Lysate |
1414 |
ProSci |
0.1 mg |
EUR 229.2 |
Description: Pancreas tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT. |
Stomach Lysate |
1415 |
ProSci |
0.1 mg |
EUR 229.2 |
Description: Stomach tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT. |
Testis Lysate |
1416 |
ProSci |
0.1 mg |
EUR 229.2 |
Description: Testis tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT. |
Adrenal Lysate |
1417 |
ProSci |
0.1 mg |
EUR 229.2 |
Description: Adrenal tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT. |
Skin Lysate |
1419 |
ProSci |
0.1 mg |
EUR 229.2 |
Description: Skin tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT. |
Eye Lysate |
1420 |
ProSci |
0.1 mg |
EUR 229.2 |
Description: Eye tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT. |
Trachea Lysate |
1422 |
ProSci |
0.1 mg |
EUR 229.2 |
Description: Trachea tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT. |
To check the belief of intra-subject (tumor) variation, we current and carry out exams of multi-set sphericity and multi-set identification of covariance buildings throughout topics (tumor varieties). We display by both theoretical and empirical research that the exams have good properties. We utilized the proposed exams on The Cancer Genome Atlas (TCGA) and examined covariance buildings for the gene expressions throughout a number of tumor varieties.