Ectopic expression of an expansin-like B gene from wild Arachis enhances tolerance to both abiotic and biotic stresses

Posted on by Perry
Ectopic expression of an expansin-like B gene from wild Arachis enhances tolerance to both abiotic and biotic stresses
Plant expansins are structural cell wall-loosening proteins implicated in a number of developmental processes and responses to environmental constraints and pathogen an infection. To date, there may be restricted details about the organic operate of Expansins-like B (EXLBs), one of the smallest and less-studied subfamilies of plant expansins. In the current examine, we performed a useful evaluation of the wild Arachis AdEXLB8 gene in transgenic tobacco (Nicotiana tabacum) vegetation to make clear its putative position in mediating protection responses to abiotic and biotic stresses.
First, its cell wall localization was confirmed in vegetation expressing AdEXLB8:eGFP fusion, whereas nanomechanical assays indicated cell wall reorganization and reassembly due to AdEXLB8 overexpression with out compromising the phenotype. We additional demonstrated that AdEXLB8 elevated tolerance not solely to remoted abiotic (drought) and biotic (Sclerotinia sclerotiorum and Meloidogyne incognita) stresses but in addition to their mixture.
The jasmonate and abscisic acid signaling pathways have been clearly favored in transgenic vegetation, exhibiting an activated antioxidative protection system. In addition to modifications within the biomechanical properties of the cell wall, we suggest that AdEXLB8 overexpression interferes with phytohormone dynamics main to a protection primed state, which culminates in plant protection responses in opposition to remoted and mixed abiotic and biotic stresses.

Ddx20, DEAD field helicase 20, is crucial for the differentiation of oligodendrocyte and upkeep of myelin gene expression

Oligodendrocytes kind myelin sheaths that encompass axons, contributing to saltatory conduction and correct central nervous system (CNS) operate. Oligodendrocyte progenitor cells (OPCs) are generated in the course of the embryonic stage and differentiate into myelinating oligodendrocytes postnatally. Ddx20 is a multifunctional, DEAD-box helicase concerned in a number of mobile processes, together with transcription, splicing, microRNA biogenesis, and translation.
Although defects in every of these processes lead to irregular oligodendrocyte differentiation and myelination, the involvement of Ddx20 in oligodendrocyte terminal differentiation stays unknown. To tackle this query, we used Mbp-Cre mice to generate Ddx20 conditional knockout (cKO) mice to permit for the deletion of Ddx20 from mature oligodendrocytes. Mbp-Cre;Ddx20 cKO mice demonstrated small physique sizes, behavioral abnormalities, muscle weak point, and quick lifespans, with mortality by the age of 2 months outdated.
Histological analyses demonstrated vital reductions within the quantity of mature oligodendrocytes and drastic reductions within the expression ranges of myelin-associated mRNAs, similar to Mbp and Plp at postnatal day 42. The quantity of OPCs didn’t change. A skinny myelin layer was noticed for large-diameter axons in Ddx20 cKO mice, based mostly on electron microscopic evaluation.
A bromodeoxyuridine (BrdU) labeling experiment demonstrated that terminal differentiation was perturbed from ages 2 weeks to 7 weeks within the CNS of Mbp-Cre;Ddx20 cKO mice. The activation of mitogen-activated protein (MAP) kinase, which promotes myelination, was downregulated within the Ddx20 cKO mice based mostly on immunohistochemical detection. These outcomes point out that Ddx20 is an important issue for terminal differentiation of oligodendrocytes and upkeep of myelin gene expression.

SUMO Paralog Specific Functions Revealed via Systematic Analysis of Human Knockout Cell Lines and Gene Expression Data

The small ubiquitin-related modifiers (SUMOs) regulate practically each facet of mobile operate, from gene expression within the nucleus to ion transport on the plasma membrane. In people, the SUMO pathway has 5 SUMO paralogs with sequence homologies that vary from 45% to 97%. SUMO1 and SUMO2 are probably the most distantly associated paralogs, and additionally the perfect studied.
To what extent SUMO1, SUMO2 and the opposite paralogs impart distinctive and non-redundant results on mobile features, nonetheless, has not been systematically examined and is due to this fact not totally understood. For occasion, knockout research in mice have revealed conflicting necessities for the paralogs throughout improvement and research in cell tradition have relied largely on transient paralog overexpression or knockdown.
To tackle the prevailing hole in understanding, we first analyzed SUMO paralog gene expression ranges in regular human tissues and discovered distinctive patterns of SUMO1-3 expression throughout 30 tissue varieties, suggesting paralog-specific features in grownup human tissues. To systematically determine and characterize distinctive and non-redundant features of the SUMO paralogs in human cells, we subsequent used CRISPR-Cas9 to knock out SUMO1 and SUMO2 expression in osteosarcoma (U2OS) cells.
Analysis of these knockout cell traces revealed important features for SUMO1 and SUMO2 in regulating mobile morphology, PML nuclear physique construction, responses to proteotoxic and genotoxic stress, and management of gene expression. Collectively, our findings reveal non-redundant regulatory roles for SUMO1 and SUMO2 in controlling important mobile processes and present a foundation for extra exact SUMO-targeting therapies.
Ectopic expression of an expansin-like B gene from wild Arachis enhances tolerance to both abiotic and biotic stresses

High-dimensional covariance matrices exams for analyzing multi-tumor gene expression information

By amassing a number of units per topic in microarray information, gene units evaluation requires characterize intra-subject variation utilizing gene expression profiling. For every topic, the info might be written as a matrix with the totally different subsets of gene expressions (e.g. a number of tumor varieties) indexing the rows and the genes indexing the columns.

FYN (NM_153047) Human Over-expression Lysate
E45H17092-2 20 ug
EUR 395

FYN (NM_153048) Human Over-expression Lysate
E45H14827-2 each
EUR 395

FYN (NM_002037) Human Over-expression Lysate
LS002534 100ug
EUR 960
Description: Transient overexpression lysate of FYN oncogene related to SRC, FGR, YES (FYN), transcript variant 1

EP Reagent Biuret Reagent - 100ML
1011601 1L
EUR 59.4

PEROXIDE BLOCKING REAGENT Reagent
GWB-Q00308 50 ml Ask for price

EP Reagent Iodoplatinate Reagent - 200ML
1046300 200ML
EUR 502.2

EP Reagent Molybdovanadic Reagent - 100ML
1056700 100ML
EUR 59.4

EP Reagent Methoxyphenylacetic Reagent - 100ML
1053601 100ML
EUR 490.05

Protein expression
CRO-4-Ind each Ask for price

EP Reagent Phosphomolybdotungstic Reagent - 100ML
1065000 100ML
EUR 226.8

RFP expression Adenovirus, in vivo ready
AVP001-PBS 1x1011 IFU/ml x 50ul
EUR 455
Description: pre-made RFP expression adenovirus, provided in PBS solution.

CFP expression Adenovirus, in vivo ready
AVP002-PBS 1x1011 IFU/ml x 50ul
EUR 455
Description: pre-made CFP expression adenovirus, provided in PBS solution.

GFP expression Adenovirus, in vivo ready
AVP011-PBS 1x1011 IFU/ml x 50ul
EUR 455
Description: pre-made GFP expression adenovirus, provided in PBS solution.

YFP expression Adenovirus, in vivo ready
AVP012-PBS 1x1011 IFU/ml x 50ul
EUR 455
Description: pre-made YFP expression adenovirus, provided in PBS solution.

BFP expression Adenovirus, in vivo ready
AVP017-PBS 1x1011 IFU/ml x 50ul
EUR 455
Description: pre-made BFP expression adenovirus, provided in PBS solution.

AVIDIN/BIOTIN BLOCKING REAGENT Reagent
GWB-Q00289 30 ml Ask for price

Gordon-McLeod Reagent (Oxidase reagent)
R026-100ML 1 unit
EUR 7.76
Description: Gordon-McLeod Reagent (Oxidase reagent)

Oxidase Reagent (Gordon-Macleod Reagent)
76207 100 ml
EUR 3.38
Description: Part B

YLEX Expression Kit
FYY201-1KT 1 kit Ask for price

EP Reagent Sulfomolybdic Reagent R3 - 1L
1086500 1L
EUR 398.25

TRIpure Reagent (same as Trizol Reagent)
MBS356001-INQUIRE INQUIRE Ask for price

h OCT4 expression Adenovirus, in vivo ready
AVP013-PBS 1x1011 IFU/ml x 50ul
EUR 455
Description: pre-made adenovirus express human stem cell factor, OCT4, provided in PBS solution for in vivo application.

h SOX2 expression Adenovirus, in vivo ready
AVP014-PBS 1x1011 IFU/ml x 50ul
EUR 455
Description: pre-made adenovirus express human stem cell factor, SOX2, provided in PBS solution for in vivo application.

293 Expression MAX-1
EXP-711-11 1ml
EUR 218
Description: 293 Expression MAX-1 is expressed from - -.

h LIN28 expression Adenovirus, in vivo ready
AVP015-PBS 1x1011 IFU/ml x 50ul
EUR 455
Description: pre-made adenovirus express human stem cell factor, LIN28, provided in PBS solution for in vivo application.

Total RNA Isolation Reagent (Reagent Based)
MBS402052-100mL 100mL
EUR 235

Total RNA Isolation Reagent (Reagent Based)
MBS402052-4Reactions 4Reactions
EUR 165

CNGA2 Expression vector
60642 20 µg
EUR 900
Description: The CNGA2 expression vector is designed to express human cyclic nucleotide-gated cation channel 2 (CNGA2) in mammalian cells.

CNGA2 Expression vector
GWB-PSFA61 20ug Ask for price

Genomic DNA Isolation Reagent (Reagent Based)
MBS402050-100mL 100mL
EUR 255

Genomic DNA Isolation Reagent (Reagent Based)
MBS402050-4Reactions 4Reactions
EUR 185

pYLEX1 - Expression Vector
FYY203-5MG 5mg Ask for price

LEXSYcon2.1 Expression Kit
EGE-1310ble 1Kit
EUR 979.85
Description: for constitutive cytosolic or secretory protein expression

LEXSYcon2.1 Expression Kit
EGE-1310bsd 1Kit
EUR 979.85
Description: for constitutive cytosolic or secretory protein expression

LEXSYcon2.1 Expression Kit
EGE-1310hyg 1Kit
EUR 979.85
Description: for constitutive cytosolic or secretory protein expression

LEXSYcon2.1 Expression Kit
EGE-1310neo 1Kit
EUR 979.85
Description: for constitutive cytosolic or secretory protein expression

LEXSYcon2.1 Expression Kit
EGE-1310pac 1Kit
EUR 979.85
Description: for constitutive cytosolic or secretory protein expression

LEXSYcon2.1 Expression Kit
EGE-1310sat 1Kit
EUR 979.85
Description: for constitutive cytosolic or secretory protein expression

Blunt E1 Expression Kit
abx098098-100l 100 µl
EUR 712.5

Blunt E1 Expression Kit
abx098098-10rxns 10 rxns
EUR 560.4

Blunt E1 Expression Kit
abx098098-1ml 1 ml Ask for price

Blunt E1 Expression Kit
abx098098-200l 200 µl Ask for price

Blunt E2 Expression Kit
abx098873-100l 100 µl
EUR 712.5

Blunt E2 Expression Kit
abx098873-10rxns 10 rxns
EUR 560.4

Blunt E2 Expression Kit
abx098873-1ml 1 ml Ask for price

Blunt E2 Expression Kit
abx098873-200l 200 µl Ask for price

RFP expression Adenovirus
AVP001 1x109 IFU/ml x 200ul
EUR 206.5
Description: pre-made RFP expression adenovirus, provided in DMEM medium.

CFP expression Adenovirus
AVP002 1x109 IFU/ml x 200ul
EUR 206.5
Description: pre-made CFP expression adenovirus, provided in DMEM medium.

GFP expression Adenovirus
AVP011 1x109 IFU/ml x 200ul
EUR 206.5
Description: pre-made GFP expression adenovirus, provided in DMEM medium.

YFP expression Adenovirus
AVP012 1x109 IFU/ml x 200ul
EUR 206.5
Description: pre-made YFP expression adenovirus, provided in DMEM medium.

BFP expression Adenovirus
AVP017 1x109 IFU/ml x 200ul
EUR 206.5
Description: pre-made BFP expression adenovirus, provided in DMEM medium.

LEXSinduce3 Expression Kit
EGE-1410ble 1Kit
EUR 2296.43
Description: for inducible cytosolic or secretory protein expression

LEXSinduce3 Expression Kit
EGE-1410blecherry 1Kit
EUR 2296.43
Description: for inducible cytosolic or secretory protein expression

LEXSinduce3 Expression Kit
EGE-1410neo 1Kit
EUR 2296.43
Description: for inducible cytosolic or secretory protein expression

LEXSinduce4 Expression Kit
EGE-1420blecherry 1Kit
EUR 2296.43
Description: for inducible cytosolic or secretory protein expression

Rac1 Expression Vector Set
STA-454 1 kit
EUR 1765.2
Description: Rac1 Expression Vector Set contains 3 vectors: Rac wild type, T17N dominant negative mutant, and G12V constitutively active mutant.

RhoA Expression Vector Set
STA-456 1 kit
EUR 1765.2
Description: RhoA Expression Vector Set contains 3 vectors: RhoA wild type, T19N dominant negative mutant, and G14V constitutively active mutant.

Plant Total RNA Isolation Reagent (Reagent Based)
MBS402053-100mL 100mL
EUR 245

Plant Total RNA Isolation Reagent (Reagent Based)
MBS402053-4Reactions 4Reactions
EUR 165

OPN expression inhibitor 1
HY-146064 10 mg
EUR 2272.76
Description: OPN expression inhibitor 1 (Compound 11) is an osteopontin (OPN) expression inhibitor. OPN expression inhibitor 1 can be used for breast cancer research[1].

OPN expression inhibitor 1
T62820-10mg 10mg Ask for price
Description: OPN expression inhibitor 1

OPN expression inhibitor 1
T62820-1g 1g Ask for price
Description: OPN expression inhibitor 1

OPN expression inhibitor 1
T62820-1mg 1mg Ask for price
Description: OPN expression inhibitor 1

OPN expression inhibitor 1
T62820-50mg 50mg Ask for price
Description: OPN expression inhibitor 1

OPN expression inhibitor 1
T62820-5mg 5mg Ask for price
Description: OPN expression inhibitor 1

Cdc42 Expression Vector Set
STA-455 1 kit
EUR 1765.2
Description: Cdc42 Expression Vector Set contains 3 vectors: Cdc42 wild type, T17N dominant negative mutant, and Q61L constitutively active mutant.

Plant Genomic DNA Isolation Reagent (Reagent Based)
MBS402051-100mL 100mL
EUR 245

Plant Genomic DNA Isolation Reagent (Reagent Based)
MBS402051-4Reactions 4Reactions
EUR 165

h FAP Expression Lentivirus
LVP1307 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: FAP, containing a RFP-Blasticidin dual selection marker.

h CD1 Expression Lentivirus
LVP1320 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: CD1, containing a RFP-Blasticidin dual selection marker.

m FAP Expression Lentivirus
LVP1326 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for mouse target: FAP, containing a RFP-Blasticidin dual selection marker.

h VIM Expression Lentivirus
LVP1357 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: VIM, containing a RFP-Blasticidin dual selection marker.

h PXN Expression Lentivirus
LVP1358 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: PXN, containing a RFP-Blasticidin dual selection marker.

m CD8 Expression Lentivirus
LVP1363 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for mouse target: CD8, containing a RFP-Blasticidin dual selection marker.

h TPO Expression Lentivirus
LVP1371 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: TPO, containing a RFP-Blasticidin dual selection marker.

h WAS Expression Lentivirus
LVP1429 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: WAS, containing a RFP-Blasticidin dual selection marker.

m PGR Expression Lentivirus
LVP1455 1x10^7 IFU/ml x 200ul
EUR 346.5
Description: Pre-made over-expression lentivirus for mouse target: PGR containing a RFP-Blasticidin dual selection marker.

h MAG Expression Lentivirus
LVP1485 1x10^7 IFU/ml x 200ul
EUR 346.5
Description: Pre-made over-expression lentivirus for human target: MAG, containing a RFP-Blasticidin dual selection marker.

h FST Expression Lentivirus
LVP1518 1x10^8 IFU/ml x 200ul
EUR 455
Description: Pre-made lentivirus express human FST gene, containing a RFP-Blasticidin dual selection marker.

h IL2 Expression Lentivirus
LVP293 1x107 IFU/ml x 200ul
EUR 276.5
Description: Lentivirus express a human IL2 gene with a Blasticidin-RFP fusion marker (Dual selection).

h ADA Expression Lentivirus
LVP923 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: ADA, containing a RFP-Blasticidin dual selection marker.

h PBK Expression Lentivirus
LVP095 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made Lentivirus express human PBK gene, carrying a RFP-Blasticidin fusion marker (Dual selection).

h IL6 Expression Lentivirus
LVP1144 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: HDAC1, containing a RFP-Blasticidin dual selection marker.

h CD4 Expression Lentivirus
LVP1152 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: CD4, containing a RFP-Blasticidin dual selection marker.

h IL4 Expression Lentivirus
LVP1161 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: IL4, containing a RFP-Blasticidin dual selection marker.

h IL7 Expression Lentivirus
LVP1162 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: IL7, containing a RFP-Blasticidin dual selection marker.

pAAV-MCS Expression Vector
MBS169528-001mg 0.01mg
EUR 695

pAAV-MCS Expression Vector
MBS169528-5x001mg 5x0.01mg
EUR 2955

pAAV-MCS Expression Vector
VPK-410 10 µg
EUR 444

FlashBAC - Baculovirus Expression System(24 reactions)
GWB-EB1FF8 Kit Ask for price

FlashBAC - Baculovirus Expression System (96 reactions)
GWB-6C34E3 Kit Ask for price

FlashBAC - Baculovirus Expression System (5 reactions)
GWB-7676BB Kit Ask for price

ExoPure? Reagent (Overall Exosome Isolation, urine)
M1003-25 each
EUR 992.4

ExoPure? Reagent (Overall Exosome Isolation, urine)
M1003-50 each
EUR 1083.6

h OCT4 expression Adenovirus
AVP013 1x109 IFU/ml x 200ul
EUR 206.5
Description: pre-made adenovirus express human stem cell factor, OCT4, provided in DMEM medium.

h SOX2 expression Adenovirus
AVP014 1x109 IFU/ml x 50ul
EUR 206.5
Description: pre-made adenovirus express human stem cell factor, SOX2, provided in DMEM medium.

h CBX7 Expression Lentivirus
LVP1308 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: CBX7, containing a RFP-Blasticidin dual selection marker.

h ACE2 Expression Lentivirus
LVP1310 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: ACE2, containing a RFP-Blasticidin dual selection marker.

h Rab7 Expression Lentivirus
LVP1315 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: Rab7, containing a RFP-Blasticidin dual selection marker.

h Rab5 Expression Lentivirus
LVP1316 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: Rab5, containing a RFP-Blasticidin dual selection marker.

m ASPA Expression Lentivirus
LVP1317 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for mouse target: ASPA, containing a RFP-Blasticidin dual selection marker.

h CD44 Expression Lentivirus
LVP1318 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: CD44, containing a RFP-Blasticidin dual selection marker.

h MFN2 Expression Lentivirus
LVP1327 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: MFN2, containing a RFP-Blasticidin dual selection marker.

h ANO1 Expression Lentivirus
LVP1344 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: ANO1 containing a RFP-Blasticidin dual selection marker.

h FGL2 Expression Lentivirus
LVP1346 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: FGL2, containing a RFP-Blasticidin dual selection marker.

h CCR2 Expression Lentivirus
LVP1354 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: CCR2, containing a RFP-Blasticidin dual selection marker.

h NEFL Expression Lentivirus
LVP1360 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: NEFL, containing a RFP-Blasticidin dual selection marker.

h NOS2 Expression Lentivirus
LVP1367 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: NOS2, containing a RFP-Blasticidin dual selection marker.

h BMI1 Expression Lentivirus
LVP1372 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: BMI1, containing a RFP-Blasticidin dual selection marker.

h PSCA Expression Lentivirus
LVP1374 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: PSCA, containing a RFP-Blasticidin dual selection marker.

h POLQ Expression Lentivirus
LVP1421 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: POLQ containing a RFP-Blasticidin dual selection marker.

h ARSA Expression Lentivirus
LVP1425 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: ARSA, containing a RFP-Blasticidin dual selection marker.

h IDUA Expression Lentivirus
LVP1426 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: IDUA, containing a RFP-Blasticidin dual selection marker.

h SGSH Expression Lentivirus
LVP1427 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: SGSH, containing a RFP-Blasticidin dual selection marker.

h CYBB Expression Lentivirus
LVP1430 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: CYBB, containing a RFP-Blasticidin dual selection marker.

h CAV1 Expression Lentivirus
LVP1431 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: CAV1, containing a RFP-Blasticidin dual selection marker.

m INS2 Expression Lentivirus
LVP1456 1x10^7 IFU/ml x 200ul
EUR 346.5
Description: Pre-made over-expression lentivirus for mouse target: INS2 containing a RFP-Blasticidin dual selection marker.

h ROR1 Expression Lentivirus
LVP1458 1x10^7 IFU/ml x 200ul
EUR 346.5
Description: Pre-made over-expression lentivirus for human target: ROR1, containing a RFP-Blasticidin dual selection marker.

h DGKA Expression Lentivirus
LVP1468 1x10^7 IFU/ml x 200ul
EUR 346.5
Description: Pre-made over-expression lentivirus for human target: DGKA, containing a RFP-Blasticidin dual selection marker.

h REST_HA Expression Lentivirus
LVP1475 1x10^7 IFU/ml x 200ul
EUR 346.5
Description: Pre-made over-expression lentivirus for human target: REST, containing a RFP-Blasticidin dual selection marker.

h UBR7 Expression Lentivirus
LVP1483 1x10^7 IFU/ml x 200ul
EUR 346.5
Description: Pre-made over-expression lentivirus for human target: UBR7, containing a RFP-Blasticidin dual selection marker.

h MMP1 Expression Lentivirus
LVP1516 1x10^8 IFU/ml x 200ul
EUR 455
Description: Pre-made lentivirus express human MMP1 gene, containing a RFP-Blasticidin dual selection marker.

h BDNF Expression Lentivirus
LVP1520 1x10^8 IFU/ml x 200ul
EUR 455
Description: Pre-made lentivirus express human BDNF gene, containing a RFP-Blasticidin dual selection marker.

m CCL5 Expression Lentivirus
LVP1619 1x10^8 IFU/ml x 200ul
EUR 455
Description: Pre-made lentivirus express mouse CCL5 gene, containing a RFP-Blasticidin dual selection marker.

h TET2 Expression Lentivirus
LVP875 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made lentivirus express human target: TET2 (tet methylcytosine dioxygenase 2). It contains a RFP-Blasticidin dual selection marker.

h TET3 Expression Lentivirus
LVP876 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for expressing human target: TET3 (tet methylcytosine dioxygenase 3), [alternative names: hCG_40738]. The sub-cloned codon sequence is identical (100% match) to CDS region in NCBI ID: NM_001287491.1 . It also contains a RFP-Blasticidin dual selection marker.

h CDR1 Expression Lentivirus
LVP917 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: CDR1, containing a RFP-Blasticidin dual selection marker.

h CD47 Expression Lentivirus
LVP918 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: CD47, containing a RFP-Blasticidin dual selection marker.

h ESR1 Expression Lentivirus
LVP924 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: ESR1, containing a RFP-Blasticidin dual selection marker.

r Syn1 Expression Lentivirus
LVP925 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for rat target: Syn1, containing a RFP-Blasticidin dual selection marker.

h NME4 Expression Lentivirus
LVP932 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: NME4, containing a RFP-Blasticidin dual selection marker.

h EGFR Expression Lentivirus
LVP1142 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: EGFR, containing a RFP-Blasticidin dual selection marker.

h CD8a Expression Lentivirus
LVP1151 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: CD8a, containing a RFP-Blasticidin dual selection marker.

h PIGF Expression Lentivirus
LVP1154 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: PIGF, containing a RFP-Blasticidin dual selection marker.

h BRAF Expression Lentivirus
LVP1156 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: BRAF, containing a RFP-Blasticidin dual selection marker.

h ROS1 Expression Lentivirus
LVP1158 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: ROS1, containing a RFP-Blasticidin dual selection marker.

h CD3E Expression Lentivirus
LVP1163 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: IL7, containing a RFP-Blasticidin dual selection marker.

h KLK3 Expression Lentivirus
LVP1171 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: KLK3, containing a RFP-Blasticidin dual selection marker.

h NEK6 Expression Lentivirus
LVP1182 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: NEK6, containing a RFP-Blasticidin dual selection marker.

h NEK7 Expression Lentivirus
LVP1183 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: NEK7, containing a RFP-Blasticidin dual selection marker.

h STM2 Expression Lentivirus
LVP1210 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: STM2, containing a RFP-Blasticidin dual selection marker.

H-Ras Expression Vector Set
STA-457 1 kit
EUR 1765.2
Description: H-Ras Expression Vector Set contains 3 vectors: H-Ras wild type, T19N dominant negative mutant, and G12V constitutively active mutant.

h LIN28 expression Adenovirus
AVP015 1x109 IFU/ml x 200ul
EUR 206.5
Description: pre-made adenovirus express human stem cell factor, LIN28, provided in DMEM medium.

h FADS2 Expression Lentivirus
LVP1319 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: FADS2, containing a RFP-Blasticidin dual selection marker.

h OVOL2 Expression Lentivirus
LVP1322 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: OVOL2, containing a RFP-Blasticidin dual selection marker.

h APOA1 Expression Lentivirus
LVP1324 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: APOA1, containing a RFP-Blasticidin dual selection marker.

h SOX10 Expression Lentivirus
LVP1325 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: SOX10, containing a RFP-Blasticidin dual selection marker.

h P2RY1 Expression Lentivirus
LVP1328 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: P2RY1, containing a RFP-Blasticidin dual selection marker.

h TUSC2 Expression Lentivirus
LVP1343 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: TUSC2, containing a RFP-Blasticidin dual selection marker.

h NLRP3 Expression Lentivirus
LVP1350 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: NLRP3, containing a RFP-Blasticidin dual selection marker.

h CCL19 Expression Lentivirus
LVP1353 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: CCL19, containing a RFP-Blasticidin dual selection marker.

h Sirt2 Expression Lentivirus
LVP1373 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: Sirt2, containing a RFP-Blasticidin dual selection marker.

h EPCAM Expression Lentivirus
LVP1375 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: EPCAM, containing a RFP-Blasticidin dual selection marker.

h PDE6B Expression Lentivirus
LVP1423 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: PDE6B, containing a RFP-Blasticidin dual selection marker.

h ABCA4 Expression Lentivirus
LVP1424 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: ABCA4, containing a RFP-Blasticidin dual selection marker.

h NAGLU Expression Lentivirus
LVP1428 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: NAGLU, containing a RFP-Blasticidin dual selection marker.

h ACOD1 Expression Lentivirus
LVP1432 1x10^7 IFU/ml x 200ul
EUR 276.5
Description: Over-expression lentivirus for human target: ACOD1, containing a RFP-Blasticidin dual selection marker.

h SIRPA Expression Lentivirus
LVP1459 1x10^7 IFU/ml x 200ul
EUR 346.5
Description: Pre-made over-expression lentivirus for human target: SIRPA, containing a RFP-Blasticidin dual selection marker.

h RIOK1 Expression Lentivirus
LVP1469 1x10^7 IFU/ml x 200ul
EUR 346.5
Description: Pre-made over-expression lentivirus for human target: RIOK1, containing a RFP-Blasticidin dual selection marker.

h HDAC8 Expression Lentivirus
LVP1482 1x10^7 IFU/ml x 200ul
EUR 346.5
Description: Pre-made over-expression lentivirus for human target: HDAC8, containing a RFP-Blasticidin dual selection marker.

h CD226 Expression Lentivirus
LVP1484 1x10^7 IFU/ml x 200ul
EUR 346.5
Description: Pre-made over-expression lentivirus for human target: CD226, containing a RFP-Blasticidin dual selection marker.

h TAOK1 Expression Lentivirus
LVP1509 1x10^8 IFU/ml x 200ul
EUR 455
Description: Pre-made lentivirus express human TAOK1 gene, containing a RFP-Blasticidin dual selection marker.

h CD155 Expression Lentivirus
LVP1512 1x10^8 IFU/ml x 200ul
EUR 455
Description: Pre-made lentivirus express human CD155 gene, containing a RFP-Blasticidin dual selection marker.

h GSTA1 Expression Lentivirus
LVP1514 1x10^8 IFU/ml x 200ul
EUR 455
Description: Pre-made lentivirus express human GSTA1 gene, containing a RFP-Blasticidin dual selection marker.

h GSTA2 Expression Lentivirus
LVP1515 1x10^8 IFU/ml x 200ul
EUR 455
Description: Pre-made lentivirus express human GSTA2 gene, containing a RFP-Blasticidin dual selection marker.

m CXCL9 Expression Lentivirus
LVP1620 1x10^8 IFU/ml x 200ul
EUR 455
Description: Pre-made lentivirus express mouse CXCL9 gene, containing a RFP-Blasticidin dual selection marker.

h TACC3 Expression Lentivirus
LVP594 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made optional inducible lentiviral particles for expressing human target: h TACC3 (alternative name: ERIC-1; ERIC1). The sub-cloned codon sequence is identical (100% match) to CDS region in NCBI ID: NM_006342.2. Particles also contains a RFP-Blasticidin dual selection marker.

h GPNMB Expression Lentivirus
LVP921 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: GPNMB, containing a RFP-Blasticidin dual selection marker.

h DECR1 Expression Lentivirus
LVP927 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: DECR1, containing a RFP-Blasticidin dual selection marker.

h DECR2 Expression Lentivirus
LVP928 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: DECR2, containing a RFP-Blasticidin dual selection marker.

h NMRK1 Expression Lentivirus
LVP930 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: NMRK1, containing a RFP-Blasticidin dual selection marker.

h PITX3 Expression Lentivirus
LVP931 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: PITX3, containing a RFP-Blasticidin dual selection marker.

h ZRSR2 Expression Lentivirus
LVP1118 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for expressing human target: ZRSR2 (zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2), [alternative names: U2AF1-RS2; U2AF1L2; U2AF1RS2; URP; ZC3H22]. The sub-cloned codon sequence is identical (100% match) to CDS region in NCBI ID: NM_005089. It also contains a RFP-Blasticidin dual selection marker.

h HDAC1 Expression Lentivirus
LVP1143 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: HDAC1, containing a RFP-Blasticidin dual selection marker.

h VEGFB Expression Lentivirus
LVP1146 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: HDAC1, containing a RFP-Blasticidin dual selection marker.

h PARP1 Expression Lentivirus
LVP1149 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: HDAC1, containing a RFP-Blasticidin dual selection marker.

h IL3RA Expression Lentivirus
LVP1150 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made over-expression lentivirus for human target: IL3RA, containing a RFP-Blasticidin dual selection marker.

h PTCH1 Expression Lentivirus
LVP1155 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: PTCH1, containing a RFP-Blasticidin dual selection marker.

h SART3 Expression Lentivirus
LVP1159 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: SART3, containing a RFP-Blasticidin dual selection marker.

h TIGIT Expression Lentivirus
LVP1160 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: TIGIT, containing a RFP-Blasticidin dual selection marker.

h EDNRA Expression Lentivirus
LVP1165 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: EDNRA containing a RFP-Blasticidin dual selection marker.

h Foxp3 Expression Lentivirus
LVP1172 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: Foxp3, containing a RFP-Blasticidin dual selection marker.

m RIKEN Expression Lentivirus
LVP1174 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for mouse target: RIKEN, containing a RFP-Blasticidin dual selection marker.

h APLP2 Expression Lentivirus
LVP1177 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: APLP2, containing a RFP-Blasticidin dual selection marker.

h PCSK9 Expression Lentivirus
LVP1178 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: PCSK9, containing a RFP-Blasticidin dual selection marker.

h NTSR1 Expression Lentivirus
LVP1179 1x107 IFU/ml x 200ul
EUR 276.5
Description: Pre-made over-expression lentivirus for human target: NTSR1, containing a RFP-Blasticidin dual selection marker.

pscAAV-MCS Expression Vector
VPK-430 10 µg
EUR 776.4
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

N.N.C.D.-reagent
N632003 1g
EUR 1200
Description: 6035-19-4
To check the belief of intra-subject (tumor) variation, we current and carry out exams of multi-set sphericity and multi-set identification of covariance buildings throughout topics (tumor varieties). We display by both theoretical and empirical research that the exams have good properties. We utilized the proposed exams on The Cancer Genome Atlas (TCGA) and examined covariance buildings for the gene expressions throughout a number of tumor varieties.

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