Description: Recombinant Human Poliovirus receptor(PVR) expressed in in vitro E.coli expression system

Description: Recombinant Human Poliovirus receptor(PVR),partial expressed in E.coli

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Poliovirus Receptor (PVR) in serum, plasma, tissue homogenates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Poliovirus Receptor (PVR) in serum, plasma, tissue homogenates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Poliovirus Receptor (PVR) in serum, plasma, tissue homogenates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Poliovirus Receptor (PVR) in serum, plasma, tissue homogenates and other biological fluids.

Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Poliovirus Receptor (PVR) in samples from serum, plasma, tissue homogenates and other biological fluids with no significant corss-reactivity with analogues from other species.

Description: Quantitativesandwich ELISA kit for measuring Human Poliovirus receptor (PVR) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Description: Quantitativesandwich ELISA kit for measuring Human Poliovirus receptor(PVR) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Description: Recombinant Human Poliovirus Receptor expressed in: E.coli

Description: Recombinant Rat Poliovirus Receptor expressed in: E.coli

Description: Quantitative sandwich ELISA for measuring Human Poliovirus receptor (PVR) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Human Poliovirus receptor (PVR) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Human Poliovirus receptor (PVR) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: A sandwich ELISA kit for detection of Poliovirus Receptor from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Description: PVR Human Recombinant produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 331 amino acids (21-343 a.a.) and having a molecular mass of 36.1kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa). PVR is expressed with an 8 amino acids His tag at C-Terminus and purified by proprietary chromatographic techniques. 

Description: A Rabbit polyclonal antibody against Rat Poliovirus Receptor (PVR)

Description: A Rabbit polyclonal antibody against Human, Mouse Poliovirus Receptor (PVR)

Description: A Rabbit polyclonal antibody against Rat Poliovirus Receptor (PVR). This antibody is labeled with APC.

Description: A Rabbit polyclonal antibody against Rat Poliovirus Receptor (PVR). This antibody is labeled with Biotin.

Description: A Rabbit polyclonal antibody against Rat Poliovirus Receptor (PVR). This antibody is labeled with Cy3.

Description: A Rabbit polyclonal antibody against Rat Poliovirus Receptor (PVR). This antibody is labeled with FITC.

Description: A Rabbit polyclonal antibody against Rat Poliovirus Receptor (PVR). This antibody is labeled with HRP.

Description: A Rabbit polyclonal antibody against Rat Poliovirus Receptor (PVR). This antibody is labeled with PE.

Description: A Rabbit polyclonal antibody against Human, Mouse Poliovirus Receptor (PVR). This antibody is labeled with APC.

Description: A Rabbit polyclonal antibody against Human, Mouse Poliovirus Receptor (PVR). This antibody is labeled with Biotin.

Description: A Rabbit polyclonal antibody against Human, Mouse Poliovirus Receptor (PVR). This antibody is labeled with Cy3.

Description: A Rabbit polyclonal antibody against Human, Mouse Poliovirus Receptor (PVR). This antibody is labeled with FITC.

Description: A Rabbit polyclonal antibody against Human, Mouse Poliovirus Receptor (PVR). This antibody is labeled with HRP.

Description: A Rabbit polyclonal antibody against Human, Mouse Poliovirus Receptor (PVR). This antibody is labeled with PE.

Description: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Description: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Description: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Description: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Description: A Rabbit polyclonal antibody against Human, Mouse Poliovirus Receptor (PVR). This antibody is labeled with APC-Cy7.

Description: A Rabbit polyclonal antibody against Rat Poliovirus Receptor (PVR). This antibody is labeled with APC-Cy7.

Description: Rabbit polyclonal to Poliovirus receptor

Description: Mouse polyclonal to Poliovirus receptor

Description: Description of target: Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytoxicity of activated NK cells. May also promote NK cell-target cell modular exchange, and PVR transfer to the NK cell. This transfer is more important in some tumor cells expressing a lot of PVR, and may trigger fratricide NK cell activation, providing tumors with a mechanism of immunoevasion. Plays a role in mediating tumor cell invasion and migration.2 Publications <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More…</a></p> Manual assertion based on experiment iniRef.17"CD155/PVR plays a key role in cell motility during tumor cell invasion and migration."_x005F_x005F_x000D_Sloan K.E., Eustace B.K., Stewart J.K., Zehetmeier C., Torella C., Simeone M., Roy J.E., Unger C., Louis D.N., Ilag L.L., Jay D.G._x005F_x005F_x000D_BMC Cancer 4:73-73(2004) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION.Ref.21"PVR (CD155) and Nectin-2 (CD112) as ligands of the human DNAM-1 (CD226) activating receptor: involvement in tumor cell lysis."_x005F_x005F_x000D_Pende D., Bottino C., Castriconi R., Cantoni C., Marcenaro S., Rivera P., Spaggiari G.M., Dondero A., Carnemolla B., Reymond N., Mingari M.C., Lopez M., Moretta L., Moretta A._x005F_x005F_x000D_Mol. Immunol. 42:463-469(2005) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION. (Microbial infection) Acts as a receptor for poliovirus. May play a role in axonal transport of poliovirus, by targeting virion-PVR-containing endocytic vesicles to the microtubular network through interaction with DYNLT1. This interaction would drive the virus-containing vesicle to the axonal retrograde transport (PubMed:2538245). Acts as a receptor for pseudorabies virus (PubMed:9616127). Is prevented to reach cell surface upon infection by human cytomegalovirus /HHV-5, presumably to escape immune recognition of infected cell by NK cells (PubMed:15640804).3 Publications <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More…</a></p> Manual assertion based on experiment iniRef.1"Cellular receptor for poliovirus: molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily."_x005F_x005F_x000D_Mendelsohn C.L., Wimmer E., Racaniello V.R._x005F_x005F_x000D_Cell 56:855-865(1989) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION (MICROBIAL INFECTION), INTERACTION WITH POLIOVIRUS CAPSID PROTEINS.Ref.9"Entry of alphaherpesviruses mediated by poliovirus receptor-related protein 1 and poliovirus receptor."_x005F_x005F_x000D_Geraghty R.J., Krummenacher C., Cohen G.H., Eisenberg R.J., Spear P.G._x005F_x005F_x000D_Science 280:1618-1620(1998) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION (MICROBIAL INFECTION), INTERACTION WITH PSEUDORAVIES VIRUS GD PROTEIN.Ref.22"Downregulation of natural killer cell-activating ligand CD155 by human cytomegalovirus UL141."_x005F_x005F_x000D_Tomasec P., Wang E.C., Davison A.J., Vojtesek B., Armstrong M., Griffin C., McSharry B.P., Morris R.J., Llewellyn-Lacey S., Rickards C., Nomoto A., Sinzger C., Wilkinson G.W._x005F_x005F_x000D_Nat. Immunol. 6:181-188(2005) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION (MICROBIAL INFECTION), INTERACTION WITH HHV-5 UL141. ;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 6.0 pg/mL

Description: Description of target: CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that in humans is encoded by the PVR gene. It is mapped to 19q13.31. The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: <50pg/ml

Description: Description of target: The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.063ng/mL

Description: Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains, a transmembrane segment, and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension between epithelial cells. Alternate splicing of the PVR mRNA yields four different isoforms ( alpha, beta , gamma , and delta) with identical extracellular domains.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Poliovirus Receptor Related Protein 1 (PVRL1) in Tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Poliovirus Receptor Related Protein 1 (PVRL1) in Tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Poliovirus Receptor Related Protein 1 (PVRL1) in Tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Poliovirus Receptor Related Protein 1 (PVRL1) in Tissue homogenates, cell lysates and other biological fluids.

Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Poliovirus Receptor Related Protein 1 (PVRL1) in samples from Tissue homogenates, cell lysates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Poliovirus Receptor Related Protein 4 (PVRL4) in serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Poliovirus Receptor Related Protein 4 (PVRL4) in serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Poliovirus Receptor Related Protein 4 (PVRL4) in serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Poliovirus Receptor Related Protein 4 (PVRL4) in serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Poliovirus Receptor Related Protein 4 (PVRL4) in samples from serum, plasma, tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Description: A sandwich quantitative ELISA assay kit for detection of Human Poliovirus Receptor Related Protein 1 (PVRL1) in samples from tissue homogenates, cell lysates or other biological fluids.

Description: A sandwich quantitative ELISA assay kit for detection of Human Poliovirus Receptor Related Protein 1 (PVRL1) in samples from tissue homogenates, cell lysates or other biological fluids.

Description: A sandwich quantitative ELISA assay kit for detection of Human Poliovirus Receptor Related Protein 4 (PVRL4) in samples from serum, plasma, tissue homogenates or other biological fluids.

Description: A sandwich quantitative ELISA assay kit for detection of Human Poliovirus Receptor Related Protein 4 (PVRL4) in samples from serum, plasma, tissue homogenates or other biological fluids.

Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

Description: For quantitative detection of human CD155/PVR in cell culture supernates, serum and plasma (heparin, EDTA).